I don't need software to be 'pretty' (ugh!), I need good workflow. > I'll go with that over something that's prettier. Perhaps Negative Lab Pro (although I haven't tried it myself, since it requires Lightroom). SilverFast used to be not that much better - not even in the latest versions, from what I have read (and their license policy is simply awful as well). Your best bet might be scanning RAW (DNG) with whatever software you have and using something modern to process the resulting RAW files. VueScan's UI is simply bad, no other words for it.
Scanning with software that is two decades old and doesn't want to change (what author of VueScan said about its UI, which is simply just awful) or is frequently bugged (SilverFast, according to some reviews) is painful. Unfortunately, SilverFast (last time I used it, few versions back, when my version still worked with then current computers, refused to upgrade afterwards for their ridiculous prices) looks like something from the 1990s, not that much better.
While VueScan does really great job of talking to many otherwise unsupported scanners, the whole UI looks and works like something from the 1980s (it's awful).